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Paper-Based Rapid Diagnostic Test Strip

This project demonstrates how a paper-based rapid diagnostic test strip uses capillary action to move a liquid sample and produce a visible color change. It introduces the basic working principle behind many modern point-of-care diagnostic tests.

Paper-Based Rapid Diagnostic Test Strip
Project Story

What I made
I made a simple paper-based rapid diagnostic test strip that moves liquid through paper using capillary action. The strip produces a visible color change to demonstrate how rapid diagnostic tests work.

Why I made it
I made this project to show how low-cost paper-based diagnostic devices can provide quick and simple testing without expensive laboratory equipment. It was inspired by the rapid test kits used in healthcare around the world.

What I learned
I learned how paper-based rapid tests move liquid without electricity or pumps by using capillary action. I also learned how simple color changes can provide quick diagnostic information. This project improved my observation, experimental design, and problem-solving skills while introducing me to an important biotechnology technology. The paper test strip successfully transported the liquid through the paper and produced visible color changes in the reaction zones, demonstrating the basic principle of rapid diagnostic tests used in healthcare.

Materials & Components

coffee filter paper Wax crayon White cardstock Food coloring Dropper Scissors Glue Transparent tape Ruler Pencil

How to Make It

  1. 1
    Cut the filter paper into a long strip.
  2. 2
    Draw simple wax barriers to guide the liquid.
  3. 3
    Create one sample pad at the bottom.
  4. 4
    Create two reaction zones near the top.
  5. 5
    Place a drop of colored water on the sample pad.
  6. 6
    Observe the liquid moving upward by capillary action.
  7. 7
    Record the color changes in the reaction zones.
  8. 8
    Compare the results and explain how the strip works.
Photos
The completed paper-based rapid test strip showing liquid flow and a visible color change.
Final paper-based rapid diagnostic test strip prototype.
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